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I'm just going to touch on the subject because there are so many things I could go on about, so let's just start with an overview.
HERE ARE 2 TYPES OF LINEWORK: A PENCIL ROUGH AND A CLEANED UP INK
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GREAT LINE WORK CAN ENHANCE GREAT DRAWINGS
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A lot of other inkers tended to flatten out Jack's work and make the images harder to read. To me, the work then looked too stylized, less alive. Some people like that better, though.
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LINES DON'T EXIST BY THEMSELVES
A line isn't important for its own sake. There are some artists who think having a big bold clean line is practically the art itself, and the drawing it describes is unimportant - as in many modern fake-UPA style cartoons.
If you have an uninteresting or ugly drawing underneath, no amount of thick clean lines can hide it-at least not from me.
On the other hand, great drawings can also be ruined by poor line work. Each animator, layout artist and cleanup artist should all understand and feel how to do warm descriptive lines that draw attention to the good qualities in the drawing they are bordering.
LINES CAN HURT DRAWINGS AS EASILY AS THEY CAN HELP THEM
Then there are styles that purposely use wiggly 
I'm not even sure if this is for real. Maybe it's someone's idea of satire.
or scratchy lines-maybe to make you know you are looking at drawings, maybe to be ugly on purpose, I don't know.
I'm not even sure if this is for real. Maybe it's someone's idea of satire.
Many artists, as they get older lose their line quality. I know I can't draw as "clean" as I could in my 20s. That's why I rely on younger inkers and clean up people-but I train them to know where to put their clean lines without "losing the life" of the original roughs.
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By the 1980s, sensitive artistic line work was a thing of the past.
COMPARE POPEYE IN THE 30S TO POPEYE AND EVERYTHING ELSE IN THE 80S
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LINES ARE YOUR DRAWINGS' SERVANTS
If you have a grasp of your drawing principles, then your lines can do a lot to bring out the elements of your drawings.
Like Pete Emslie
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http://cartooncave.blogspot.com/2007/09/angry-girlfriend.html
His lines are very appealing - but not merely appealing for their own sake. They make sense. They are there to help describe the drawing underneath. They are slightly loose and rough, but a cleanup artist would have no trouble knowing where to put the final lines, and how much weight to give them.
His lines are artistic, but they are subservient to the drawings they are describing.
They aren't just one skinny even line that travels around the outline.
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Preston Blair also has beautiful flowing lines.
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From a rough but defined sketch like the Sody one above, a good inker (like Brian Romero) can work his magic and give you a smooth, alive, organic being.
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Lines, like forms obey a hierarchy of importance. Some parts of your drawing are more important than others and need thicker lines.
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It's not quite that simple and not completely a science. There are some general rules to help out, but then part of it is instinct.
SHANE GLINES
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Shane Glines used to ink a lot of my stuff and he knew exactly how to enhance what the drawing itself was trying to say.
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You admired his lines, but you saw a character first, not a bunch of disconnected details.
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***Note to Mitch-
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